Sequence dependence of protein isoprenylation
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چکیده
منابع مشابه
Protein isoprenylation in Trypanosoma brucei brucei.
Trypanosoma brucei is a digenetic protozoan parasite presenting a public health hazard in certain areas of Africa; it is transmitted between mammals (bloodstream form (BSF)) by tsetse flies (procyclic form (PCF)). We have an ongoing interest in small GTP proteins in T. brucei, and these are commonly isoprenylated. Many isoprenylated proteins belong to the rab family and include ras; the isopren...
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Molecular dynamics (MD) simulations are used to probe the origin of the unexpected temperature dependence of salt accumulation in the C-terminal region of the protein human lymphotactin. As in previous MD simulations, sodium ions accumulate in an enhanced manner near the C-terminal helix at the lower temperature, while the temperature dependence of chloride accumulation is much weaker and sligh...
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682 25 Griinler, J., Olsson, J. M. and Dallner, G. (1995) 29 Reiss, Y., Brown, M. S. and Goldstein, J. I , . (1992) FEBS Lett. 358, 230-232 26 Shipton, C. A., Parmryd, I., Swiezewska, E., 30 Forman, €3. M., Goode, I<., Chen, J., Oro, A. E., Andersson, B. and Dallner, G. (1995) J. Biol. Bradley, D. J., Perlmann, ‘I-., Noonan, I). J., Burka, Chem. 270, 566-572 1, . T., McMorris, ‘I7., I,amph, W. ...
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Isoprenylation is an important posttranslational modification of proteins in eukaryotic cells, as it facilitates protein–membrane and protein–protein interactions. In plants, isoprenylated proteins (which include a number of small GTPases and the G-protein g-subunit) are involved in phytohormone signaling, meristem maintenance, cell cycle regulation, and stress responses (Crowell, 2000; Johnson...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1991
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)98729-6